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Frequently Asked Questions
Does InheriNext® support trio analysis?
Yes, InheriNext® Edge (RUO) supports Trio & Family analysis. Leverage family analysis tools like pedigree charts and segregation algorithms to explore inheritance patterns and assess the clinical significance of variants in a family context.
What variant types are supported by InheriNext®?
InheriNext® and InheriNext® Edge (RUO) support WGS: SNV, Indel, CNV, MT, SV, STR; WES: SNV, Indel, CNV; WES + MT: SNV, Indel, CNV, MT.
(Note: SNV= single nucleotide variant; Indel = insertion/deletions; CNV = copy number variations; MT = mitochondrial; SV = structural variants; STR = short tandem repeats).
Does InheriNext® support secondary analysis?
Yes, InheriNext® supports both FASTQ and VCF files as starting points for your variant interpretation. InheriNext® processes your data through an optimized pipeline with parallel computing for speed. This pipeline generates intermediate reports detailing key metrics such as FASTQ quality, alignment to the reference sequence, and target region coverage (excluding WGS).
Does InheriNext® follow ACMG guidelines?
Yes, InheriNext® evaluates the pathogenicity of your variants based on ACMG guidelines, which classify variants based on 28 criteria. InheriNext® automates up to 17 ACMG criteria and elaborates on reasons for those criteria.
How can I test InheriNext® capabilities?
We offer a four-stage process designed to ensure InheriNext meets your specific needs and integrates seamlessly into your workflow: 1) a personal demonstration, 2) a trial, with sample data and your data. 3) a pilot license and 4) a custom integration into your operations.
Can I get a demo of InheriNext®?
Click the “Book a Demo” button at the top of the page, schedule a personalized demonstration between you and our scientists at Compass. In the comments, please provide information so we can tailor the presentation to your requirements and confirm data compatibility. We want to ensure that your time during the demonstration answers your questions and allows you to experience InheriNext® user-friendly interface and interpretation capabilities.
Can I get a trial of InheriNext®?
Prior to a trial, you should have a demonstration, to familiarize yourself with the platform. Following the demonstration, you’ll receive a trial account with access to either your own data or our sample datasets (VCF or FASTQ files, depending on your workflow). Providing aligned phenotypic data enhances the trial’s value. (During the process, we may request access to provide optimal support). Click the “Book a Demo” button to schedule a demonstration.
Can I get a pilot license for InheriNext®?
Following the trial period, we can provide a pilot license to test the integration of InheriNext® into your institution. Our staged pilot program includes additional training and allows for customization discussions to ensure a smooth transition. Click on “Contact Us” to find out more!
What does a contract for InheriNext® look like?
We offer transparent pricing models (annual licenses, per-report options, and collaborative partnerships) and are happy to discuss contract terms at any stage of the trial. Our goal is a mutually beneficial relationship that prioritizes patient care. Customization options include report generation, panel support for various sequencing protocols, and seamless IT integrations.
Can I create my own presets of phenotypes or gene panels?
Yes, for customized presets, you can create them under Profile > Panel > Phenotype Set or Gene Panel set.
Can reports be customized for our institution and how much does it cost?
Yes, our reports sections are customizable with toggled on/off buttons. For further customization needs, we’d love to assist you, please feel free to “Contact Us”!