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AI-powered Software Designed to Streamline NGS Genetic Testing
We help you organize patient data, build custom databases, and manage every NGS process from the moment you receive your FASTQ files
InheriNext® is made from the following product modules
Workflow Runner
From Raw Data to Actionable Insights
Automate the conversion of FASTQ to VCF with speed and accuracy. Workflow Runner simplifies your NGS pipeline, saves time and reduces complexity.
Problem It Solves
FASTQ to VCF analysis can be computationally intensive and algorithmically challenging
Limited access to resources and expertise creates bottlenecks and delays results
Sequencing technology and targeting create unique requirements per analysis
How It Works
Optimized algorithms through scalable & parallel computing
Clean user interface helps you upload data with customizable parameters
Results / Benefits
Saves hours of manual work.
Accurately identifies complex variant calls of SNPs, Indels, CNVs, and structural variants
Accelerates the path to meaningful analysis
Phenotype Gene Prioritizer
Find What Matters Most
Quickly identify & prioritize variants linked to specific phenotypes. Let AI-driven insights guide your discovery of inherited disease causes.
Problem It Solves
Only a handful of relevant variant candidates among millions
Error prone application of complex professional guidelines
Ever changing databases and algorithms require continuous updates
How It Works
AI Models continuously update resources to automate the automatable and to highlight variants that require additional scrutiny
Phenotype and genotype data combine to create the strongest case for variant interpretation
Results / Benefits
Optimized variant identification: benchmark shows >98% of the cases causative variant identified and explained within top-10
YOUR time is dedicated to tasks that require humans
Provides confidence in prioritization with AI-driven insights.
Diagnostic tests
Focuses on identifying genetic variants linked through case exhibited phenotypes or in silico gene panels that match recorded inherited diseases for precise diagnosis.
Proactive tests
Prioritizes genes to assess potential risks and predispositions to genetic conditions.
Filter
Refines large datasets to highlight the most relevant variants for targeted analysis.
Monitor
Bookmarks variants of interest for report manageament or further explorations.
Report
Generates detailed and customizable reports to summarize findings and insights effectively.
PhenoVarDB
Organize, Store, and Collaborate
Effortlessly manage and store your genetic analysis results. PhenoVarDB empowers you to group data into cohorts and revisit findings with ease.
Problem It Solves
Limited tools for longitudinal data tracking
Lack of efficient storage and computing resources for personal databases
Difficulty collaborating or grouping data
How It Works
Search cases by variants, genes, phenotypes, diseases
Optimize through big query & parallel computing
Cohort grouping for comparative analysis & variant matching across patients
Results / Benefits
Simplifies data organization
Detects common variant from local population
Enables better collaboration
Expert
InheriNext® Expert facilitates an additional stage of interpretation, through a chat experience that utilize a domain-specific AI/LLMs algorthm trained with medical texts.
Expert (in Beta) aims to answer with relevant information to help users eventually differentiate between candidate variants & the true cause of the phenotype.
Problem It Solves
The selection of reportable variants from candidate variants often requires more data and support
To communicate variant significance requires constant resource updates and sensitivity to all stake holders
How It Works
Interactive “Chat” interface connects to InheriNext® data sources
Integrates clinical real patient & community surveys through gLMs, RTL technology & trained domain-specific LLM models
Results / Benefits
Faster, simpler interpretation of genetic data
Reference-based support for reported variants
InheriNext® is...
Immediate
In a matter of minutes, InheriNext® offers precise variant candidates and a range of functions for inherited disease analysis.
Resourceful
Two ways to utilize InheriNext®'s AI-based variant prioritizing strategies: you can find causative SNPs and INDELs using either HPO-based phenotypes or gene panels.
User Friendly
InheriNext®’s user friendly interface is the result of careful design, allowing you to intuitive understand the results. This ensures that you invest your time in analysis, not learning software!
Multi-Purpose
InheriNext® encompasses numerous prediction & population models and cross-compares variant and disease databases. The tools required for prioritizing & interpreting variants are folded into one platform that we continue to evolve to meet the requirements of exploding data, professional guidelines, and global regulation.
