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Frank

Ong

Frank

Ong

Chief Executive Officer

Background

Prenetics,

Chief Medical Officer (CMO),

2021-2024

Illumina,

Associate Director of Medical Affairs,

2012-2015

Biography

With a rare blend of clinical depth and technical vision, Frank leads Compass Bioinformatics as CEO – bringing together a global team of AI engineers, software developers, and genetics professionals to build cutting-edge platforms for analyzing next-generation sequencing data in rare and inherited diseases. His leadership spans top roles at Prenetics, ACT Genomics, Everly Health, Illumina, QIAGEN, and Roche. A physician-scientist by training, Frank completed his Clinical Molecular Genetics fellowship at UCLA, holds an MD from USC, and trained in biodesign at Stanford. Frank’s mission is bold but clear: to transform patient care through AI-driven, privacy-conscious bioinformatics. Here’s what our advisors Gregory & Heath say about him: “Frank has broad experience in healthcare with a particularly deep focus on applying cutting edge technologies to real clinical issues… Frank has a great combination of knowing what’s right for the patient and what’s right for the business.” “Frank is a rare blend of physician-scientist, innovator, and leader—equally fluent in clinical medicine, molecular genetics, and AI-driven bioinformatics. He has a gift for translating complex science into practical, high-impact solutions, especially in genomics and precision medicine. As a leader, Frank has deep expertise yet remains grounded, able to align cross-functionally and drive execution across disciplines and continents.“ Now, under his leadership, Compass Bioinformatics is delivering smarter, faster, and more impactful genomic solutions to the world.

Team Members

Scientific Advisory Board

Chief Strategy Officer

Chief Information Officer

Chief Executive Officer

PRODUCT PORTFOLIO

PRODUCT PORTFOLIO